Contrave is a prescription weight loss medication that is used along with a reduced-calorie diet and increased physical activity to help adults who are overweight or have obesity lose weight.
The medication is a combination of two active ingredients: bupropion and naltrexone. Bupropion is an antidepressant medication that can also help reduce cravings and withdrawal symptoms associated with nicotine and other substances. Naltrexone is a medication that is commonly used to treat alcohol and opioid dependence, but when combined with bupropion, it can help reduce food cravings and decrease appetite.
The exact mechanism of action of Contrave is not fully understood, but it is believed to work in two ways. First, it may increase the activity of certain brain chemicals that help control appetite and eating behavior. Second, it may decrease the reward and pleasure associated with eating, which can reduce overeating and help with weight loss.
It’s important to note that Contrave is not a “magic pill” for weight loss, and it is not recommended for everyone. It is only approved for use in adults with a body mass index (BMI) of 30 or greater (obese), or a BMI of 27 or greater (overweight) with at least one weight-related medical condition such as high blood pressure, type 2 diabetes, or high cholesterol.
As with any medication, Contrave may have side effects. Common side effects may include nausea, constipation, headache, dizziness, and insomnia. More serious side effects are rare, but may include seizures, suicidal thoughts or actions, or increased blood pressure and heart rate.
Contrave should only be taken under the supervision of a healthcare provider, and it should be used in combination with a healthy diet and exercise plan. It is not recommended for pregnant or breastfeeding women, or for people with a history of seizures, eating disorders, or uncontrolled high blood pressure.